2-Aminoadamantane hydrochloride → HCID 59516151, compound

HRID 1799403Notes

Reaction equation

HRID 1799403 reaction equation
[CH3:1][O:2][C:3]([CH2:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]2[C:16]([S:17][CH2:18][CH2:19][CH3:20])=[C:15]([C:21]([OH:23])=O)[CH:14]=[N:13]2)=[CH:8][CH:7]=1)=[O:4].Cl.[CH:25]12[CH2:34][CH:29]3[CH2:30][CH:31]([CH2:33][CH:27]([CH2:28]3)[CH:26]1[NH2:35])[CH2:32]2.C(SC1N(C2C=CC(C(OC)=O)=CC=2)N=CC=1C(N1CCC(C2C=CC=CC=2C(F)(F)F)C1)=O)CC>>[CH:25]12[CH2:34][CH:29]3[CH2:30][CH:31]([CH2:33][CH:27]([CH2:28]3)[CH:26]1[NH:35][C:21]([C:15]1[CH:14]=[N:13][N:12]([C:9]3[CH:8]=[CH:7][C:6]([CH2:5][C:3]([O:2][CH3:1])=[O:4])=[CH:11][CH:10]=3)[C:16]=1[S:17][CH2:18][CH2:19][CH3:20])=[O:23])[CH2:32]2

Participants

4

Reactant 3

HCID 253312-Aminoadamantane hydrochlorideHCID 59516100HCID 59516100, compoundHCID 59516146HCID 59516146, compound2×

Product 1

HCID 59516151HCID 59516151, compound

Procedure

Prepared from 1-[4-(methoxycarbonylmethyl)phenyl]-5-propylsulfanyl-pyrazole-4-carboxylic acid (Intermediate #35) and 2-adamantylamine hydrochloride by the same procedure as used for Intermediate #6.

Sources & evidence

ORD record
ord-612ffc11d56b4dae8dfef27d2c809ffc
Source dataset
uspto-grants-2013_01
Patent number
US08344016B2

Reaction notes

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