HRID1799432

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)c1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccc(Cl)c(C(F)(F)F)c1

HCID59516137

未命名化合物

2 次

结构：CCOC(=O)c1ccc(-n2ncc(C(=O)NC3C4CC5CC(C4)CC3C5)c2C(C)(C)C)c(C)c1

HCID59516141

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)c1ccc(-n2ncc(C(=O)NC3C4CC5CC(C4)CC3C5)c2C(C)(C)C)cc1C(F)(F)F

HCID59516069

未命名化合物

PROCEDURE

实验过程

Ethyl 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]-2-(trifluoromethyl)benzoate was prepared from N-(2-adamantyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]-5-tert-butyl-pyrazole-4-carboxamide (Intermediate #118) by the same process used for Intermediate #113.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f88df5ad07e94244adbd179a4b9b6164
来源数据集: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08344016B2
来源说明: uspto-grants-2013_01

反应 SMILES

[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:23]3[CH:28]=[CH:27][C:26](Cl)=[C:25]([C:30]([F:33])([F:32])[F:31])[CH:24]=3)[C:18]=1[C:19]([CH3:22])([CH3:21])[CH3:20])=[O:13])[CH2:8]2.C12CC3CC(CC(C3)C1NC(C1C=NN(C3C=CC([C:60]([O:62][CH2:63][CH3:64])=[O:61])=CC=3C)C=1C(C)(C)C)=O)C2>>[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:23]3[CH:28]=[CH:27][C:26]([C:60]([O:62][CH2:63][CH3:64])=[O:61])=[C:25]([C:30]([F:33])([F:32])[F:31])[CH:24]=3)[C:18]=1[C:19]([CH3:22])([CH3:21])[CH3:20])=[O:13])[CH2:8]2