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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1799432Generated: November 1, 2026

N-(2-adamantyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]-5-tert-butyl-pyrazole-4-carboxamide → Ethyl 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]-2-(trifluoromethyl)benzoate

https://huagongshe.com/reaction/1799432

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-adamantyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]-5-tert-butyl-pyrazole-4-carboxamideHCID 59516137—
ReactantHCID 59516141HCID 59516141—
ProductEthyl 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]-2-(trifluoromethyl)benzoateHCID 59516069—

Reaction Steps

Ethyl 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]-2-(trifluoromethyl)benzoate was prepared from N-(2-adamantyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]-5-tert-butyl-pyrazole-4-carboxamide (Intermediate #118) by the same process used for Intermediate #113.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08344016B2
Source datasetuspto-grants-2013_01
ORD IDord-f88df5ad07e94244adbd179a4b9b6164
Source noteuspto-grants-2013_01