HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-2-(furan-2-yl)imidazo[1,2-b]pyridazine → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[2-(2-furyl)imidazo[1,2-b]pyridazin-6-yl]amino}thiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-2-(furan-2-yl)imidazo[1,2-b]pyridazine | HCID 11746128 | — |
| Reactant | 2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide | HCID 59525619 | — |
| Product | 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[2-(2-furyl)imidazo[1,2-b]pyridazin-6-yl]amino}thiophene-3-carboxamide | HCID 44552734 | — |
Reaction Steps
The title compound was prepared as described in Example 1, Step 5 using 6-chloro-2-(2-furyl)imidazo[1,2-b]pyridazine (61.9 mg, 0.282 mmol) and 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide as starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344144B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-41c2afc77898425d9fb26b3afb404af6 |
| Source note | uspto-grants-2013_01 |