6-Chloro-N-isopropylimidazo[1,2-b]pyridazine-2-carboxamide → 6-({3-(Aminocarbonyl)-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-thienyl}amino)-N-isopropylimidazo[1,2-b]pyridazine-2-carboxamide

Participants

Reaction Steps

The title compound was prepared as described in Example 1, Step 5 using 6-chloro-N-isopropylimidazo[1,2-b]pyridazine-2-carboxamide (149 mg, 0.62 mmol) and 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (177 mg, 0.57 mmol) as starting materials.

Provenance & Evidence