Bromide ion → 2-(4-Bromo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-phenylethanol

HRID 180067Notes

Reaction equation

HRID 180067 reaction equation
[Br-:38].[CH3:28][N:29]([CH3:30])[P:31]([N:32]([CH3:33])[CH3:34])[N:35]([CH3:36])[CH3:37].[CH3:40][C:41]#[N:42].[Li+:39].[O:20]=[C:21]1[N:22]([Br:27])[C:23](=[O:24])[CH2:25][CH2:26]1.[OH:1][CH:2]([CH2:3][n:4]1[n:5][cH:6][c:7]2[c:8]1[n:9][cH:10][nH:11][c:12]2=[O:13])[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[OH:1][CH:2]([CH2:3][n:4]1[n:5][cH:6][c:7]2[c:8]1[n:9][cH:10][n:11][c:12]2[Br:27])[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1

Participants

7

Reactant 6

HCID 259Bromide ionHCID 6342AcetonitrileHCID 15355Hexamethylphosphorous triamideHCID 28486Lithium ionHCID 67184N-bromobutanimideHCID 1363835291-(2-Hydroxy-2-phenylethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

Product 1

HCID 866099072-(4-Bromo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-phenylethanol

Sources & evidence

ORD record
ord-10671a8ef59d4e0bb0605b32d11ac30f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…