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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1800840Generated: October 31, 2026

Isoindoline → HCID 59321360, compound

https://huagongshe.com/reaction/1800840

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoindolineHCID 422478—
Reactant3-Fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)picolinic acidHCID 59200397—
ProductHCID 59321360HCID 59321360—

Reaction Steps

Following the amide bond forming procedure given in example 37, 3-fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)picolinic acid (intermediate B in example 1) and isoindoline were reacted to give the title compound. LC/MS (M+H)+: 464. Ret. time: 1.66 min. (Condition M); analytical HPLC Ret. time: 17.03 min (Condition N).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08343999B2
Source datasetuspto-grants-2013_01
ORD IDord-13d61c0bf3804bee9ac1900a682e0d56
Source noteuspto-grants-2013_01