Ethyl Acetate → HCID 54740910, compound

HRID 1801995Notes

Reaction equation

HRID 1801995 reaction equation
[CH:1]1([C:7]2[CH:8]=[C:9]3[C:14](=[N:15][CH:16]=2)[N:13]([CH3:17])[C:12](=[O:18])[C:11]([C:19](=[O:26])[CH2:20][CH2:21][C:22]([O:24]C)=[O:23])=[C:10]3[OH:27])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[H][H].C(OCC)(=O)C>[Pd].C(O)C>[CH:1]1([C:7]2[CH:8]=[C:9]3[C:14](=[N:15][CH:16]=2)[N:13]([CH3:17])[C:12](=[O:18])[C:11]([C:19](=[O:26])[CH2:20][CH2:21][C:22]([OH:24])=[O:23])=[C:10]3[OH:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

6

Reactant 3

HCID 8857Ethyl AcetateHCID 67408283HCID 67408283, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 54740910HCID 54740910, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Methyl 4-(6-cyclohexyl-4-hydroxy-1-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)-4-oxobutanoate. The title compound is prepared by hydrogenation with palladium black in the presence of hydrogen gas in a suitable solvent such as ethyl acetate or ethanol.

Sources & evidence

ORD record
ord-4d2cca6998214df2b6139bea60e0a958
Source dataset
uspto-grants-2013_01
Patent number
US08349868B2

Reaction notes

Loading…