Hydrochloric Acid → HCID 86666021, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of {2-[(2-fluoro-ethyl)-methyl-amino]-[1,2,4]triazolo[1,5-a]pyridin-7-yl}-carbamic acid tert-butyl ester (1.7 g, 5.5 mmol) and hydrochloric acid in dioxane (4N, 39.2 ml, 156.7 mmol) was stirred at 25° C. for 16 h. Volatiles were removed in vacuo to afford N2-(2-Fluoro-ethyl)-N2-methyl-[1,2,4]triazolo[1,5-a]pyridine-2,7-diamine hydrochloride as a light yellow solid (1.3 g, 96.3%). MS: m/z=210.2 (M+H+).

Provenance & Evidence