HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azetidine → Azetidin-1-yl-(1-methyl-1H-pyrazol-4-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azetidine | HCID 10422 | — |
| Reactant | 1-Methyl-1H-pyrazole-4-carboxylic acid | HCID 643160 | — |
| Reactant | N,N,1-trimethyl-1H-pyrazole-4-carboxamide | HCID 59551573 | — |
| Product | Azetidin-1-yl-(1-methyl-1H-pyrazol-4-yl)-methanone | HCID 58446814 | — |
Reaction Steps
This compound was prepared in analogy to 1-methyl-1H-pyrazole-4-carboxylic acid dimethylamide (Example 97, step a) from 1-methyl-1H-pyrazole-4-carboxylic acid (1.0 g, 7.93 mmol) and azetidine (475 mg, 8.33 mmol). Yield: 1.31 g (92%); light yellow solid; MS: m/z=166.1 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08349824B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-92b86a5cba0441d1b0d282c96d59c8e2 |
| Source note | uspto-grants-2013_01 |