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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1802507Generated: October 31, 2026

Potassium Carbonate → HCID 59435992, compound

https://huagongshe.com/reaction/1802507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 59436087HCID 59436087—
SolventMethanolHCID 887—
ProductHCID 59435992HCID 59435992—

Reaction Steps

To a solution of N-{2,6-dichloro-4-[(trimethylsilyl)ethynyl]phenyl}-10-methoxypyrido[4,3-c]-1,6-naphthyridin-6-amine (118 mg, 0.25 mmol) in methanol (3 mL) was added K2CO3 (38.4 mg, 0.28 mmol) and stirred at room temperature overnight. The solvents were evaporated and the residue was diluted with ethyl acetate and washed with water followed by brine. The organic layer was dried with sodium sulfate, filtered and concentrated under reduced pressure to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08349865B2
Source datasetuspto-grants-2013_01
ORD IDord-d774c0604da746e39e799ff3a803f1b6
Source noteuspto-grants-2013_01