HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 59435992, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 59436087 | HCID 59436087 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59435992 | HCID 59435992 | — |
Reaction Steps
To a solution of N-{2,6-dichloro-4-[(trimethylsilyl)ethynyl]phenyl}-10-methoxypyrido[4,3-c]-1,6-naphthyridin-6-amine (118 mg, 0.25 mmol) in methanol (3 mL) was added K2CO3 (38.4 mg, 0.28 mmol) and stirred at room temperature overnight. The solvents were evaporated and the residue was diluted with ethyl acetate and washed with water followed by brine. The organic layer was dried with sodium sulfate, filtered and concentrated under reduced pressure to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08349865B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-d774c0604da746e39e799ff3a803f1b6 |
| Source note | uspto-grants-2013_01 |