Hydrochloric Acid → HCID 68634098, compound

Participants

Reaction Steps

1-BOC-3-bromo-5-(1,1-dioxo-thiomorpholine-4-yl)methyl-7-nitro-2-phenyl-1H-indole obtained in Step 3 (825 mg, 1.6 mmol) was dissolved in diethylether (5 mL), and then HCl (4M dioxane solution, 5 mL). The reaction solution was stirred for 2 hours at room temperature. At the end of the reaction, removed solvent under reduced pressure and dried to obtain 3-bromo-5-(1,1-dioxo-thiomorpholine-4-yl)methyl-7-nitro-2-phenyl-1H-indole, which was used in the next step without further purification.

Provenance & Evidence