Bicarbonate Ion → 1-(5-Bromo-2-methoxy-3-pyridinyl)-3-(3,4-dichlorophenyl)prop-2-en-1-ol

HRID 180298Notes

Reaction equation

HRID 180298 reaction equation
[Br:1][c:2]1[c:3]([O:9][CH3:10])[n:4][cH:5][c:6]([Br:8])[cH:7]1.[C:34](=[O:35])([OH:36])[O-:37].[CH2:17]([Li:18])[CH2:19][CH2:20][CH3:21].[CH3:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[Cl:22][c:23]1[cH:24][c:25]([CH:26]=[CH:27][CH:28]=[O:29])[cH:30][cH:31][c:32]1[Cl:33].[Na+:38].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[c:2]1([CH:28]([CH:27]=[CH:26][c:25]2[cH:24][c:23]([Cl:22])[c:32]([Cl:33])[cH:31][cH:30]2)[OH:29])[c:3]([O:9][CH3:10])[n:4][cH:5][c:6]([Br:8])[cH:7]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 8058HexaneHCID 135677523,5-Dibromo-2-methoxypyridineHCID 538805763,4-DichlorocinnamaldehydeHCID 178418339Butyllithium

Product 1

HCID 538790661-(5-Bromo-2-methoxy-3-pyridinyl)-3-(3,4-dichlorophenyl)prop-2-en-1-ol

Sources & evidence

ORD record
ord-0aa22a0d360a445a87cb59aa5a1f950b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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