Hexylamine → 2,5-Dimethylhexane-2,5-diyl bis(2-(hexylamino)acetate)

HRID 1802997Notes

Reaction equation

HRID 1802997 reaction equation
Cl[CH2:2][C:3]([O:5][C:6]([CH3:18])([CH2:8][CH2:9][C:10]([O:13][C:14](=[O:17])[CH2:15]Cl)([CH3:12])[CH3:11])[CH3:7])=[O:4].[NH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>C(Cl)Cl>[CH2:20]([NH:19][CH2:2][C:3]([O:5][C:6]([CH3:18])([CH2:8][CH2:9][C:10]([O:13][C:14](=[O:17])[CH2:15][NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])([CH3:12])[CH3:11])[CH3:7])=[O:4])[CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

Participants

4

Reactant 2

HCID 8102HexylamineHCID 582821502,5-Dimethylhexane-2,5-diyl bis(2-chloroacetate)

Product 1

HCID 866538362,5-Dimethylhexane-2,5-diyl bis(2-(hexylamino)acetate)

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The cleavable diol is made by the following manner. Compound (61) is reacted with 5 equivalents of 1-aminohexane (65) in methylene chloride. Wash with brine and dry to yield 2,5-dimethylhexane-2,5-diyl bis(2-(hexylamino)acetate) (66).

Workup

  1. washWash with brine
  2. customdry

Sources & evidence

ORD record
ord-59e398b68fba4a6c8498d77fe24e5e51
Source dataset
uspto-grants-2013_01
Patent number
US08349990B2

Reaction notes

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