反应详情

A mixture of 5-[(3,5-difluorobenzyl)oxy]-2-nitrobenzonitrile (1 g, 3.44 mmol) and palladium 5% on carbon (150 mg) in 1,4-dioxane (20 mL) was treated under hydrogen atmosphere (40 psi) at room temperature. After 4 hours, the mixture was filtered on a celite pad and evaporated to dryness affording 770 mg (yield 86%) of the title compound.

1. additionwas treated under hydrogen atmosphere (40 psi) at room temperature
2. filtrationthe mixture was filtered on a celite pad
3. customevaporated to dryness