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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1803968Generated: October 26, 2026

2-Oxazolidinone → 3-{5-[4-(4-Chlorobenzoyl)piperidine-1-carbonyl]pyridin-2-yl}oxazolidin-2-one

https://huagongshe.com/reaction/1803968

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
Reactant(6-Bromopyridin-3-yl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanoneHCID 58484839—
Product3-{5-[4-(4-Chlorobenzoyl)piperidine-1-carbonyl]pyridin-2-yl}oxazolidin-2-oneHCID 5475511612.8%

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 31 and using (6-bromopyridin-3-yl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanone (2 g) described in Preparation Example 23 and oxazolidin-2-one (435 mg), the title compound (260 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-ab0d7fa49e114369832fa87a904d9930
Source noteuspto-grants-2013_01