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HRID1803970

反应详情

EQUATION

反应方程式

HRID 1803970 的结构方程式

REACTANTS

反应物

2
结构：CC[C@@H]1COC(=O)N1
HCID641503

(4R)-4-ethyl-1,3-oxazolidin-2-one

C5H9NO2

结构：O=C(c1ccc(Cl)cc1)C1CCN(C(=O)c2ccc(Br)nc2)CC1
HCID58484839

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCC(C(=O)c3ccc(Cl)cc3)CC2)cn1
HCID54755118

未命名化合物

收率 61.7%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 31 and using (6-bromopyridin-3-yl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanone (2 g) described in Preparation Example 23 and (R)-4-ethyloxazolidin-2-one (300 mg) described in Preparation Example 26, the title compound (710 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 31
  3. customdescribed in Preparation Example 26