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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1803971Generated: October 26, 2026

5-Bromopyridine-2-carboxylic acid → (5-Bromopyridin-2-yl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanone

https://huagongshe.com/reaction/1803971

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromopyridine-2-carboxylic acidHCID 608544—
Reactant4-(4-Chlorobenzoyl)piperidine hydrochlorideHCID 2777114—
Product(5-Bromopyridin-2-yl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanoneHCID 5848457799.1%

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 27 and using 5-bromopyridine-2-carboxylic acid (1.2 g) and (4-chlorophenyl)piperidin-4-ylmethanone hydrochloride (1.6 g), the title compound (2.4 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-332627213511430e9f2eaad83e348404
Source noteuspto-grants-2013_01