反应详情

By reaction and treatment in the same manner as in Example 53 and using 4-(3-chloro-5-methylpyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester (9 g), which is the intermediate described in Preparation Example 48, a compound was obtained, which was treated with 4N hydrogen chloride/ethyl acetate (2 mL) to give the title compound (1.1 g).

1. customBy reaction and treatment in the same manner as in Example 53
2. customdescribed in Preparation Example 48
3. customa compound was obtained