化工社化工社 化学情報印刷レポート · 研究参考用
6-Bromonicotinic acid → (6-Bromopyridin-3-yl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Bromonicotinic acid | HCID 238932 | — |
| 反応物 | 1-(3,5-Dimethylpyridin-2-yl)piperazine | HCID 58484496 | — |
| 生成物 | (6-Bromopyridin-3-yl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484661 | 99.9% |
反応手順
By reaction and treatment in the same manner as in Preparation Example 67 and using 6-bromonicotinic acid (808 mg) and 1-(3,5-dimethylpyridin-2-yl)piperazine (765 mg) described in Preparation Example 47, the title compound (1.5 g) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08354401B2 |
| 出典データセット | uspto-grants-2013_01 |
| ORD ID | ord-dd1fcf73389147b48bd2fc583ef2e1c4 |
| 出典メモ | uspto-grants-2013_01 |