HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodobenzoyl chloride → [4-(3,5-Dimethylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodobenzoyl chloride | HCID 74373 | — |
| Reactant | 1-(3,5-Dimethylpyridin-2-yl)piperazine | HCID 58484496 | — |
| Product | [4-(3,5-Dimethylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone | HCID 58484535 | 95.6% |
Reaction Steps
By reaction and treatment in the same manner as in Preparation Example 8 and using 1-(3,5-dimethylpyridin-2-yl)piperazine (3.8 g) described in Preparation Example 47 and 4-iodobenzoyl chloride (5.3 g), the title compound (8 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-120c9017c3ce48a3b927c91a13d43446 |
| Source note | uspto-grants-2013_01 |