Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804025Generated: October 25, 2026

Ethyl 4-iodobenzoate → (R)-4-(4-ethyl-2-oxooxazolidin-3-yl)benzoic acid

https://huagongshe.com/reaction/1804025

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-iodobenzoateHCID 142891—
Reactant(4R)-4-ethyl-1,3-oxazolidin-2-oneHCID 641503—
Product(R)-4-(4-ethyl-2-oxooxazolidin-3-yl)benzoic acidHCID 58484770—

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 18 and using ethyl 4-iodobenzoate (1.4 mL) and (R)-4-ethyloxazolidin-2-one (979 mg) described in Preparation Example 26, the title compound (2.6 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-d4b4bf98a74b438da2f829860979d935
Source noteuspto-grants-2013_01