Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804026Generated: November 1, 2026

Ethyl 4-iodobenzoate → (R)-4-(2-oxo-4-propyloxazolidin-3-yl)benzoic acid

https://huagongshe.com/reaction/1804026

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-iodobenzoateHCID 142891—
Reactant(4R)-4-Propyl-2-oxazolidinoneHCID 2734859—
Product(R)-4-(2-oxo-4-propyloxazolidin-3-yl)benzoic acidHCID 58484846—

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 18 and using ethyl 4-iodobenzoate (3.2 mL) and (R)-4-propyloxazolidin-2-one (2.5 g) described in Preparation Example 29, the title compound (5.7 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-846ed9f5f6aa4559b318bb374851e081
Source noteuspto-grants-2013_01