HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-methanesulfonylbenzoic acid → (4-Bromo-2-methanesulfonylphenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-methanesulfonylbenzoic acid | HCID 2761057 | — |
| Reactant | 1-(3,5,6-Trimethylpyridin-2-yl)piperazine hydrochloride | HCID 67381052 | — |
| Product | (4-Bromo-2-methanesulfonylphenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484785 | 51.8% |
Reaction Steps
By reaction and treatment in the same manner as in Preparation Example 27 and using 4-bromo-2-methanesulfonylbenzoic acid (3.5 g) and 1-(3,5,6-trimethylpyridin-2-yl)piperazine hydrochloride (3 g) described in Preparation Example 52, the title compound (3 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-9fe689d9b5b04f5c97c15848f26a9357 |
| Source note | uspto-grants-2013_01 |