huagongshe.com
HRID1804032

反应详情

EQUATION

反应方程式

HRID 1804032 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)c1cc(Br)ccc1C(=O)O
HCID2761057

4-Bromo-2-(methylsulfonyl)benzoic acid

C8H7BrO4S

结构：Cc1cc(C2CC2)cnc1N1CCNCC1.Cl
HCID67381091

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2S(C)(=O)=O)CC1
HCID58484821

未命名化合物

收率 94.1%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 27 and using 4-bromo-2-methanesulfonylbenzoic acid (558 mg) and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine hydrochloride (508 mg) described in Preparation Example 49, the title compound (0.9 g) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 27
  3. customdescribed in Preparation Example 49