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4-Bromo-2-methanesulfonylbenzoic acid → (4-Bromo-2-methanesulfonylphenyl)[4-(3,5-dicyclopropylpyridin-2-yl)piperazin-1-yl]methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromo-2-methanesulfonylbenzoic acid | HCID 2761057 | — |
| 反応物 | 1-(3,5-Dicyclopropylpyridin-2-yl)piperazine | HCID 58484701 | — |
| 生成物 | (4-Bromo-2-methanesulfonylphenyl)[4-(3,5-dicyclopropylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484601 | 73% |
反応手順
By reaction and treatment in the same manner as in Preparation Example 38 and using 4-bromo-2-methanesulfonylbenzoic acid (2.29 g) and 1-(3,5-dicyclopropylpyridin-2-yl)piperazine (2 g) described in Preparation Example 62, the title compound (3.02 g) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08354401B2 |
| 出典データセット | uspto-grants-2013_01 |
| ORD ID | ord-51ee6f98b8294464935b355b27a0c143 |
| 出典メモ | uspto-grants-2013_01 |