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4-Iodobenzoyl chloride → [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Iodobenzoyl chloride | HCID 74373 | — |
| 反応物 | 1-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine | HCID 58484718 | — |
| 生成物 | [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone | HCID 58484841 | 90% |
反応手順
By reaction and treatment in the same manner as in Preparation Example 65 and using 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine (1.42 g) described in Preparation Example 96, 4-iodobenzoyl chloride (1.83 g), the title compound (2.63 g) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08354401B2 |
| 出典データセット | uspto-grants-2013_01 |
| ORD ID | ord-22ba39c39b1b4dbb87d1b304d413781a |
| 出典メモ | uspto-grants-2013_01 |