HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Bromo-2-fluorobenzoyl chloride → (4-Bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Bromo-2-fluorobenzoyl chloride | HCID 2734026 | — |
| Edukt | 1-(5-Ethyl-3-methylpyridin-2-yl)piperazine hydrochloride | HCID 67380924 | — |
| Produkt | (4-Bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484537 | 99,2% |
Reaktionsschritte
By reaction and treatment in the same manner as in Preparation Example 8 and using 4-bromo-2-fluorobenzoyl chloride (2.4 g) and 1-(5-ethyl-3-methylpyridin-2-yl)piperazine hydrochloride (2.4 g) described in Preparation Example 99, the title compound (4 g) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08354401B2 |
| Quelldatensatz | uspto-grants-2013_01 |
| ORD ID | ord-2bc27c99f4fa49688a7136d9952bf6d8 |
| Quellennotiz | uspto-grants-2013_01 |