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HRID1804061

反应详情

EQUATION

反应方程式

HRID 1804061 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(Br)cnc1N1CCNCC1
HCID46739270

1-(5-Bromo-3-methylpyridin-2-yl)piperazine

C10H14BrN3

结构：Cc1cc(F)ncc1C(=O)O
HCID46739274

6-Fluoro-4-methylpyridine-3-carboxylic acid

C7H6FNO2

PRODUCTS

生成物

1
结构：Cc1cc(F)ncc1C(=O)N1CCN(c2ncc(Br)cc2C)CC1
HCID58484740

未命名化合物

收率 43.4%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 69 and using 6-fluoro-4-methylnicotinic acid (931 mg) and 1-(5-bromo-3-methylpyridin-2-yl)piperazine (1.5 g), the title compound (1 g) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 69