Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804064Generated: October 25, 2026

2-Oxazolidinone → Methyl 2-(1,1-dioxoisothiazolidin-2-yl)-4-(2-oxooxazolidin-3-yl)benzoate

https://huagongshe.com/reaction/1804064

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
ReactantMethyl 4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)benzoateHCID 58484624—
ProductMethyl 2-(1,1-dioxoisothiazolidin-2-yl)-4-(2-oxooxazolidin-3-yl)benzoateHCID 5848474737.7%

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 12 and using methyl 4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)benzoate (2 g) described in Preparation Example 116 and oxazolidin-2-one (515 mg), the title compound (758 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-8f96173681e04c26ad168ce511e91c94
Source noteuspto-grants-2013_01