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HRID1804078

反应详情

EQUATION

反应方程式

HRID 1804078 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc(Br)nc1
HCID238932

6-Bromonicotinic acid

C6H4BrNO2

结构：Cc1cc(C#N)cnc1N1CCNCC1
HCID67381274

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C#N)cnc1N1CCN(C(=O)c2ccc(Br)nc2)CC1
HCID58484518

未命名化合物

收率 74.2%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 60 and using 6-bromonicotinic acid (500 mg) and 5-methyl-6-piperazin-1-ylnicotinonitrile (501 mg), the title compound (709 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 60