huagongshe.com
HRID1804079

反应详情

EQUATION

反应方程式

HRID 1804079 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(Br)ccc1C(=O)O
HCID99570

4-Bromo-2-methylbenzoic acid

C8H7BrO2

结构：Cc1cc(C#N)cnc1N1CCNCC1
HCID67381274

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(Br)ccc1C(=O)N1CCN(c2ncc(C#N)cc2C)CC1
HCID58484676

未命名化合物

收率 106.8%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 60 and using 4-bromo-2-methylbenzoic acid (215 mg) and 5-methyl-6-piperazin-1-ylnicotinonitrile (202 mg), the title compound (426 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 60