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HRID1804083

反应详情

EQUATION

反应方程式

HRID 1804083 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(F)ncc1C(=O)O
HCID46739274

6-Fluoro-4-methylpyridine-3-carboxylic acid

C7H6FNO2

结构：CCc1cnc(N2CCNCC2)c(C)c1
HCID58484578

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cnc(N2CCN(C(=O)c3cnc(F)cc3C)CC2)c(C)c1
HCID58484602

未命名化合物

收率 59.1%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 60 and using 6-fluoro-4-methylnicotinic acid (500 mg) and 1-(5-ethyl-3-methylpyridin-2-yl)piperazine (649 mg) described in Preparation Example 53, the title compound (640 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 60
  3. customdescribed in Preparation Example 53