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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804084Generated: November 1, 2026

2-Oxazolidinone → 6-(2-Oxooxazolidin-3-yl)nicotinic acid methyl ester

https://huagongshe.com/reaction/1804084

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
ReactantMethyl 6-bromopyridine-3-carboxylateHCID 13349623—
Product6-(2-Oxooxazolidin-3-yl)nicotinic acid methyl esterHCID 5848449578.8%

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 12 and using methyl 6-bromonicotinate (1 g) and oxazolidin-2-one (474 mg), the title compound (810 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-4328fde310a84dcd8457157246093512
Source noteuspto-grants-2013_01