(4S)-4-(Benzoyloxymethyl)oxazolidine-2-one → (R)-4-[4-(4-benzoyloxymethyl-2-oxooxazolidin-3-yl)benzoyl]piperazine-1-carboxylic acid tert-butyl ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(4S)-4-(Benzoyloxymethyl)oxazolidine-2-one	HCID 16213752	—
Edukt	Tert-butyl 4-(4-iodobenzoyl)piperazine-1-carboxylate	HCID 44157877	—
Produkt	(R)-4-[4-(4-benzoyloxymethyl-2-oxooxazolidin-3-yl)benzoyl]piperazine-1-carboxylic acid tert-butyl ester	HCID 58484870	90,3%

Reaktionsschritte

By reaction and treatment in the same manner as in Preparation Example 91 and using 4-(4-iodobenzoyl)piperazine-1-carboxylic acid tert-butyl ester (3.75 g) described in Preparation Example 161 and benzoic acid (R)-2-oxooxazolidin-4-ylmethyl ester (1.99 g), the title compound (4.14 g) was obtained.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08354401B2
Quelldatensatz	uspto-grants-2013_01
ORD ID	ord-d18b7af3194d468da2611bf617e3e22c
Quellennotiz	uspto-grants-2013_01