HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → 4-(4-Bromo-2-methanesulfonylbenzoyl)piperazine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | 4-Bromo-2-methanesulfonylbenzoic acid | HCID 2761057 | — |
| Product | 4-(4-Bromo-2-methanesulfonylbenzoyl)piperazine-1-carboxylic acid tert-butyl ester | HCID 58484680 | 94.2% |
Reaction Steps
By reaction and treatment in the same manner as in Preparation Example 90 and using 4-bromo-2-methanesulfonylbenzoic acid (10.2 g) and piperazine-1-carboxylic acid tert-butyl ester (7.49 g), the title compound (15.4 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-08f4a76f6f5041039384aa14dd4324ef |
| Source note | uspto-grants-2013_01 |