HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxazolidinone → 3-{2-Chloro-4-[4-(2,4-dimethylphenyl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxazolidinone | HCID 73949 | — |
| Reactant | (4-Bromo-3-chlorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone | HCID 58484864 | — |
| Product | 3-{2-Chloro-4-[4-(2,4-dimethylphenyl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one | HCID 46189945 | 57.8% |
Reaction Steps
By reaction and treatment in the same manner as in Example 1 and using (4-bromo-3-chlorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (815 mg) described in Preparation Example 3 and oxazolidin-2-one (174 mg), the title compound (478 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-b8dd6a2f786642e28d49a5febb35bd33 |
| Source note | uspto-grants-2013_01 |