HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxazolidinone → 3-{4-[4-(2-Ethyl-4-methylphenyl)piperazine-1-carbonyl]-3-methanesulfonylphenyl}oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxazolidinone | HCID 73949 | — |
| Reactant | (4-Bromo-2-methanesulfonylphenyl)[4-(2-ethyl-4-methylphenyl)piperazin-1-yl]methanone | HCID 58484563 | — |
| Product | 3-{4-[4-(2-Ethyl-4-methylphenyl)piperazine-1-carbonyl]-3-methanesulfonylphenyl}oxazolidin-2-one | HCID 67380975 | 1.2% |
Reaction Steps
By reaction and treatment in the same manner as in Example 1 and using (4-bromo-2-methanesulfonylphenyl)[4-(2-ethyl-4-methylphenyl)piperazin-1-yl]methanone (1.8 g) described in Preparation Example 15 and oxazolidin-2-one (418 mg), the title compound (22 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-870dae39a10447789cbea9d4a890ce11 |
| Source note | uspto-grants-2013_01 |