HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxazolidinone → 3-{4-[4-(2-Cyclopropyl-4-methylphenyl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxazolidinone | HCID 73949 | — |
| Reactant | [4-(2-Cyclopropyl-4-methylphenyl)piperazin-1-yl](4-iodophenyl)methanone | HCID 58484789 | — |
| Product | 3-{4-[4-(2-Cyclopropyl-4-methylphenyl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one | HCID 46190175 | 27.1% |
Reaction Steps
By reaction and treatment in the same manner as in Example 1 and using [4-(2-cyclopropyl-4-methylphenyl)piperazin-1-yl](4-iodophenyl)methanone (280 mg) described in Preparation Example 17 and oxazolidin-2-one (313 mg), the title compound (69 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-ff6acbb897ce4558ab5d1d19fcf66a52 |
| Source note | uspto-grants-2013_01 |