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HRID1804178

反应详情

EQUATION

反应方程式

HRID 1804178 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(C(=O)C2CCNCC2)c(C)c1.Cl
HCID43810626

未命名化合物

结构：C[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484719

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(C(=O)C2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C)cc3)CC2)c(C)c1
HCID67380785

未命名化合物

收率 104.5%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 49 and using (2,4-dimethylphenyl)piperidin-4-ylmethanone hydrochloride (253 mg) and (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid (211 mg) described in Preparation Example 37, the title compound (419 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 49
  2. customdescribed in Preparation Example 37