HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Methylphenoxy)piperidine → (R)-4-methyl-3-[4-(4-p-tolyloxypiperidine-1-carbonyl)phenyl]oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Methylphenoxy)piperidine | HCID 3837497 | — |
| Reactant | (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid | HCID 58484719 | — |
| Product | (R)-4-methyl-3-[4-(4-p-tolyloxypiperidine-1-carbonyl)phenyl]oxazolidin-2-one | HCID 67381285 | 77.6% |
Reaction Steps
By reaction and treatment in the same manner as in Example 52 and using 4-(p-tolyloxy)piperidine (1 g) and (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid (1.2 g) described in Preparation Example 37, the title compound (1.6 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-878a4ab351534d078c1b314cc1ef2612 |
| Source note | uspto-grants-2013_01 |