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HRID1804190

反应详情

EQUATION

反应方程式

HRID 1804190 的结构方程式

REACTANTS

反应物

2
结构：CC(C)[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484694

未命名化合物

结构：Cc1cc(C(F)(F)F)cnc1N1CCNCC1
HCID58484729

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C(F)(F)F)cnc1N1CCN(C(=O)c2ccc(N3C(=O)OC[C@H]3C(C)C)cc2)CC1
HCID67380990

未命名化合物

收率 30.7%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 29 and using (R)-4-(4-isopropyl-2-oxooxazolidin-3-yl)benzoic acid (499 mg) described in Preparation Example 18 and 1-(3-methyl-5-trifluoromethylpyridin-2-yl)piperazine (490 mg) described in Preparation Example 51, the title compound (292 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 29
  2. customdescribed in Preparation Example 51