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HRID1804192

反应详情

EQUATION

反应方程式

HRID 1804192 的结构方程式

REACTANTS

反应物

2
结构：CC(C)[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484694

未命名化合物

结构：Cc1cc(C2CC2)cnc1N1CCNCC1.Cl
HCID67381091

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3C(=O)OC[C@H]3C(C)C)cc2)CC1
HCID67380778

未命名化合物

收率 42.5%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 29 and using 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine hydrochloride (381 mg) described in Preparation Example 49 and (R)-4-(4-isopropyl-2-oxooxazolidin-3-yl)benzoic acid (374 mg) described in Preparation Example 18, the title compound (286 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 29
  2. customdescribed in Preparation Example 18