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HRID1804196

反应详情

EQUATION

反应方程式

HRID 1804196 的结构方程式

REACTANTS

反应物

2
结构：CC[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484770

未命名化合物

结构：Cc1cnc(N2CCNCC2)c(C)c1.Cl
HCID67381379

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)cc1
HCID67381186

未命名化合物

收率 38.2%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 49 and using (R)-4-(4-ethyl-2-oxooxazolidin-3-yl)benzoic acid (470 mg) described in Preparation Example 78 and 1-(3,5-dimethylpyridin-2-yl)piperazine hydrochloride (455 mg) described in Preparation Example 64, the title compound (312 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 49
  2. customdescribed in Preparation Example 64