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HRID1804203

反应详情

EQUATION

反应方程式

HRID 1804203 的结构方程式

REACTANTS

反应物

2
结构：CC[C@@H]1COC(=O)N1
HCID641503

(4R)-4-ethyl-1,3-oxazolidin-2-one

C5H9NO2

结构：Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3S(C)(=O)=O)CC2)c(C)c1
HCID58484505

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)c(S(C)(=O)=O)c1
HCID67380915

未命名化合物

收率 42.4%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 1 and using (4-bromo-2-methanesulfonylphenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (874 mg) described in Preparation Example 61 and (R)-4-ethyloxazolidin-2-one (300 mg) described in Preparation Example 26, the title compound (399 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 1
  2. customdescribed in Preparation Example 26