huagongshe.com
HRID1804224

反应详情

EQUATION

反应方程式

HRID 1804224 的结构方程式

REACTANTS

反应物

2
结构：COc1cc(N2C(=O)OC[C@H]2C)ccc1C(=O)O
HCID58484787

未命名化合物

结构：Cc1cnc(N2CCNCC2)c(C)c1.Cl
HCID67381379

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(N2C(=O)OC[C@H]2C)ccc1C(=O)N1CCN(c2ncc(C)cc2C)CC1.Cl
HCID67381134

未命名化合物

收率 37.8%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 87 and using (R)-2-methoxy-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid (1.1 g) described in Preparation Example 45 and 1-(3,5-dimethylpyridin-2-yl)piperazine hydrochloride (956 mg) described in Preparation Example 64, the title compound (731 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 87
  2. customdescribed in Preparation Example 64