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HRID1804286

反应详情

EQUATION

反应方程式

HRID 1804286 的结构方程式

REACTANTS

反应物

2
结构：O=C1NCCO1
HCID73949

2-Oxazolidinone

C3H5NO2

结构：Cc1cnc(N2CCN(C(=O)c3ccc(Cl)cc3N3[C@H](C)CCS3(=O)=O)CC2)c(C)c1
HCID58484709

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(N2CCN(C(=O)c3ccc(N4CCOC4=O)cc3N3[C@H](C)CCS3(=O)=O)CC2)c(C)c1
HCID58484744

未命名化合物

收率 15.1%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 201 and using (R)-[4-chloro-2-(3-methyl-1,1-dioxoisothiazolidin-2-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (95.1 mg) described in Preparation Example 125 and oxazolidin-2-one (17.9 mg), the title compound (15.9 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 201