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HRID1804308

反应详情

EQUATION

反应方程式

HRID 1804308 的结构方程式

REACTANTS

反应物

2
结构：O=C1NCCO1
HCID73949

2-Oxazolidinone

C3H5NO2

结构：Cc1cc(C#N)cnc1N1CCN(C(=O)c2ccc(Br)cc2F)CC1
HCID58484606

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C#N)cnc1N1CCN(C(=O)c2ccc(N3CCOC3=O)cc2F)CC1
HCID58484754

未命名化合物

收率 81.5%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 1 and using 6-[4-(4-bromo-2-fluorobenzoyl)piperazin-1-yl]-5-methylnicotinonitrile (215 mg) described in Preparation Example 134 and oxazolidin-2-one (70 mg), the title compound (178 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 1