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HRID1804338

反应详情

EQUATION

反应方程式

HRID 1804338 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)C=NC(=O)O1
HCID21464782

5,5-Dimethyloxazolin-2-one

C5H7NO2

结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(I)cc2)CC1
HCID58484841

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CC(C)(C)OC3=O)cc2)CC1
HCID58484625

未命名化合物

收率 28.3%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 110 and using [4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (447 mg) described in Preparation Example 97 and 5,5-dimethyloxazolin-2-one (138 mg) described in Preparation Example 43, the title compound (123 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 110
  2. customdescribed in Preparation Example 43