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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804343Generated: November 1, 2026

2-Oxazolidinone, 5,5-dimethyl- → 5,5-Dimethyl-3-{4-[4-(3,5,6-trimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one

https://huagongshe.com/reaction/1804343

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxazolidinone, 5,5-dimethyl-HCID 136892—
Reactant(4-Iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484793—
Product5,5-Dimethyl-3-{4-[4-(3,5,6-trimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-oneHCID 5848463925.5%

Reaction Steps

By reaction and treatment in the same manner as in Example 110 and using (4-iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone (579 mg) described in Preparation Example 176 and 5,5-dimethyloxazolidin-2-one (153 mg) described in Preparation Example 43, the title compound (143 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-7ae8c3e202c647bd961cb5e96e2f0568
Source noteuspto-grants-2013_01